A production app is generally working well with memcached and Rails 2.1, but we're seeing this error about 10 times a day:
Anyone get a solution for this? Im seeing the same thing with a rails 2.1 deploy. Tried with memcache-client gem installed locally and part of active support and both get this connection problem intermittently.
Consider switching to http://github.com/37signals/libmemcached_store 
jeremy