It these possible in Rails?

Can do any of theses (from RoR):

access a COM object
call loadlibrary
receive and send(or post) windows messages
access a native dll
access a .net dll

Thanks,
Ratnavel

Yes, but you'll probably need to use native code to do so.
This is really more of a question about Ruby than about Rails, so
you'll probably be better off asking the Ruby-Talk list, if the Google
results don't suffice to answer your further questions.

Regards,

David